TauRx to Present Two-Year Data from Phase III Trial of HMTM in Alzheimer’s Disease at the AD/PD™ 2024 Conference in March

TauRx Pharmaceuticals Ltd., a global leader in Tau-based research in Alzheimer’s disease (AD), announced today that the company will present the 24-month data from its Phase III LUCIDITY trial of hydromethylthionine mesylate (HMTM) at the upcoming AD/PD™ 2024 Alzheimer's & Parkinson's Diseases Conference from 5-9 March 2024, in Lisbon, Portugal.

Professor Claude Wischik, Co-Founder, CEO and Executive Chairman of TauRx will present data including details of the final 12-month open label phase of the study indicating maintenance of subjects with mild cognitive impairment due to Alzheimer’s at baseline cognitive scores. A panel, moderated by Dr. Serge Gauthier and including Professor Henrik Zetterberg, Professor Alistair Burns, and Dr. David Watson, will discuss the relevancy of these data and the potential impact of HMTM on people living with Alzheimer’s.

“We believe that presentation and discussion of this data represents an important step in our mission to bring people living with Alzheimer’s and their loved ones a safe and effective oral treatment that they will be able to access,” said Professor Claude Wischik. “Alzheimer’s is a global problem, one that impacts millions of people in some way at some point, and we are determined to help those impacted by this disease.”

HMTM is designed for early intervention to modify the disease, slowing progression of AD. If approved, HMTM will be the first oral, anti-tau therapy with a robust safety profile requiring minimal testing and treatment monitoring. This simplified profile will promote accessibility and affordability for people living with Alzheimer’s.

At the conference, TauRx will present the data during a moderated panel discussion at 13:50 CET on 7 March (Abstract #2363; “24-month topline results from Phase III LUCIDITY trial in AD show combined disease-modifying and symptomatic activity for HMTM”) and host an additional question and answer session on 9 March. Professor Wischik will also participate in a forum discussion “Anti-tau therapies in clinical trials—what are the challenges and opportunities for a rational therapy?” on 8 March.

TauRx has initiated regulatory engagement in the UK and the US for intended product approval. Other territories will follow in line with plans to scale commercialisation of HMTM.

For additional information, please visit: https://taurx.com/ or https://adpd.kenes.com/.

TauRx Press Release, 5th February 2024

TauRx to Present Two-Year Data from Phase III Trial of HMTM in Alzheimer’s Disease at the AD/PD™ 2024 Conference in March