The TauRx group of life science companies is focused on the development of novel treatments and diagnostics for Alzheimer's Disease (AD) and other neurodegenerative diseases.
Our team includes highly skilled and internationally recognized pharmaceutical experts in many aspects of drug development. From initial discovery through to clinical trials, data analysis and product registration, we are working together towards halting the progression of Alzheimer's, frontotemporal dementia (FTD) and other neurodegenerative diseases.
Our Protein Aggregation Inhibitors target the underlying pathology of dementia, with the aim of modifying or halting disease progression and an ultimate goal of prevention. Our lead compound, LMTX™, targets aggregation of tau, synuclein, TDP-43 and huntingtin protein. Its primary development in Alzheimer's is focused in its activity as a Tau Aggregation Inhibitor (TAI).
TauRx is incorporated in Singapore with primary research and operations in Aberdeen, Scotland.
March 2015:Treatment to target…
January 2015:First Evidence of…
September 2014:TauRx Therapeutics…
August 2014:TauRx: In the News
July 2014:TauRx Therapeutics…
First Evidence of Potential Efficacy of Tau Aggregation Inhibitor Therapy in Alzheimer’s Disease
TauRx Completes Recruitment to Phase 3 Alzheimer’s Disease Studies
The Tau-hypothesis of Alzheimer’s disease pathogenesis proposes that age-related malfunctions in the cellular processing of Tau protein, which is a normal component of healthy cells, leads to Tau protein misfolding and loss of neuronal function, then to the formation of neurotoxic aggregates and ultimately disease symptoms. See Science for more.
Alzheimer’s Innovation: In Our Hands
By 2050, nearly 104 million people [one third of the current U.S. population] are predicted to have Alzheimer’s disease, according to the World Health Organisation. This underscores the need for new treatments to halt and prevent the formation of Tau tangles - the hallmark sign of dementia. See FTD Rationale